ADVERTISEMENT
  • News
  • New York
  • Technology
  • Culture
  • Entertainment
  • Sport
  • More
    • Politics
    • Lifestyle
    • TV
    • Games
Monday, May 19, 2025
  • Login
No Result
View All Result
NEWSLETTER
FINCHANNEL
  • Home
  • Business
    • BANKS
      • GeoBanks
    • Finance
    • Insurance
    • Markets
    • Pharmacy
    • Press Releases
    • RealEstate
    • RealEstate
    • Finance
    • Insurance
    • Banks
      • GeoBanks
    • Markets
    • Press Releases
    • Personal Finance
  • World
    • Americas
    • Europe
    • Georgia
      • Media
    • Ukraine
    • Europe
    • Georgia
      • Media
    • Ukraine
    • Americas
    • UK local news
  • Travel
    • Hotels in Georgia
    • Tours in Georgia
  • Videos
    • Promos
    • Soundslides
    • TheClinics
    • TheHoteliers
    • TheUniversities
    • TheHoteliers
    • TheClinics
    • TheUniversities
    • BestWorkplaces
    • Soundslides
    • Promos
    • Banking Forum
      • Promos
      • Soundslides
      • TheClinics
      • TheHoteliers
      • TheUniversities
  • Opinion
    • Editorial
      • Analysis
      • GORBI
      • OP-ED
      • VISA Editorial
    • Analysis
    • Gorbi
    • Book reviews
  • Tech
  • Interview
  • People
    • lifestyle
    • Health & Beauty
      • Coronavirus
    • LifeStyle
    • Employment
      • MyCareer
    • Education
    • Media
    • Celebrities
  • Oil&Auto
    • Auto
    • Energy
  • EN
    • EN
    • GE
  • Home
  • Business
    • BANKS
      • GeoBanks
    • Finance
    • Insurance
    • Markets
    • Pharmacy
    • Press Releases
    • RealEstate
    • RealEstate
    • Finance
    • Insurance
    • Banks
      • GeoBanks
    • Markets
    • Press Releases
    • Personal Finance
  • World
    • Americas
    • Europe
    • Georgia
      • Media
    • Ukraine
    • Europe
    • Georgia
      • Media
    • Ukraine
    • Americas
    • UK local news
  • Travel
    • Hotels in Georgia
    • Tours in Georgia
  • Videos
    • Promos
    • Soundslides
    • TheClinics
    • TheHoteliers
    • TheUniversities
    • TheHoteliers
    • TheClinics
    • TheUniversities
    • BestWorkplaces
    • Soundslides
    • Promos
    • Banking Forum
      • Promos
      • Soundslides
      • TheClinics
      • TheHoteliers
      • TheUniversities
  • Opinion
    • Editorial
      • Analysis
      • GORBI
      • OP-ED
      • VISA Editorial
    • Analysis
    • Gorbi
    • Book reviews
  • Tech
  • Interview
  • People
    • lifestyle
    • Health & Beauty
      • Coronavirus
    • LifeStyle
    • Employment
      • MyCareer
    • Education
    • Media
    • Celebrities
  • Oil&Auto
    • Auto
    • Energy
  • EN
    • EN
    • GE
No Result
View All Result
FINCHANNEL
No Result
View All Result
Home Health&Beauty

Test for antibiotic associated kidney damage in children with cystic fibrosis identified

The FINANCIAL by The FINANCIAL
March 29, 2018
in Health&Beauty
Reading Time: 2 mins read
8
A A
0
Test for antibiotic associated kidney damage in children with cystic fibrosis identified
Share on FacebookShare on Twitter

The FINANCIAL — New research, published in Nature Scientific Reports, conducted by the University and partners highlights effective methods for identifying a common side effect in children receiving drug treatments for Cystic fibrosis.

The genetic disorder, cystic fibrosis (CF) is characterised by secondary bacterial lung infections, often by a specific resistant bacteria, Pseudomonas aeruginosa. Antibiotics known as aminoglycosides have good efficacy against this bacteria and are often used to treat these infections, according to University of Liverpool.

However, aminoglycosides are potentially damaging to the kidneys. Despite risk reduction strategies, current or recent aminoglycoside exposure is strongly associated with acute kidney injury (AKI) in children with CF.

RelatedPosts

Packaged bread can be considered ultra-processed foods

As many as 30% of people with insomnia report using alcohol as a sleep aid

A Guide for Adults Over 50

How to Deep Clean Your Air Fryer in 5 Easy Steps

Biomarkers

Current methods for assessing kidney injury rely on the measurement of serum creatinine, a measure of kidney filtration. Unfortunately this method only highlights injury once significant damage has already occurred. This is particularly dangerous for children.

To identify patients at increased risk of kidney damage there is a need for the development of improved biomarkers that not only reflect the site of toxicity, but can identify damage at an earlier stage than currently possible.

To help identify biomarkers, researchers from the Universities of Liverpool and University College London, recruited more than 150 children and young adults up to 20 years of age with a confirmed diagnosis of CF. The participants provided urine samples for measurement of specific proteins, KIM-1 and NGAL, at regular outpatient appointments, and before, during and after exposure to clinically-indicated treatment with anaminoglycoside.

See also  Packaged bread can be considered ultra-processed foods

The researchers found that the concentrations of both KIM-1 and NGAL increased during exposure to an aminoglycoside. These increases occurred in the absence of increases in serum creatinine, and therefore likely represent renal damage without loss of function, commonly termed ‘subclinical AKI’. The baseline (before treatment) concentration of KIM-1 increased with cumulative lifetime aminoglycoside exposure, suggesting it may also identify chronic renal damage.

Useful and non-invasive

The study was led by Dr Steve McWilliam a National Institute of Health Research Academic Clinical Lecturer in Paediatric Clinical Pharmacology from the University of Liverpool’s Institute of Translational Medicine based at Alder Hey Children’s NHS Foundation Trust.

Of the study Dr McWilliam said: “Our research shows that KIM-1 may be a useful, non-invasive, biomarker of acute and chronic kidney damage associated with exposure to aminoglycosides in patients with CF, but its clinical utility needs to be further evaluated in prospective studies.”

 

Related Posts

Packaged bread can be considered ultra-processed foods
Health&Beauty

Packaged bread can be considered ultra-processed foods

by The FINANCIAL
April 29, 2025
0

The FINANCIAL -- Everyday items such as breakfast cereals and mass-produced or packaged bread can be considered ultra-processed foods. This...

Read more
Chronic sleep deficiency increases insulin resistance in women, especially postmenopausal women

As many as 30% of people with insomnia report using alcohol as a sleep aid

April 16, 2025
A Guide for Adults Over 50

A Guide for Adults Over 50

April 15, 2025
How to Deep Clean Your Air Fryer in 5 Easy Steps

How to Deep Clean Your Air Fryer in 5 Easy Steps

April 3, 2025

Discussion about this post

  • Trending
  • Comments
  • Latest
Ampersand wins £22m five-year contract at London Zoo

Ampersand wins £22m five-year contract at London Zoo

June 25, 2012
U.S. Lifts Sanctions on Syria: How This Will Affect Recognition of Russia-occupied Territories?

U.S. Lifts Sanctions on Syria: How This Will Affect Recognition of Russia-occupied Territories?

May 15, 2025
U.S. Money Reserve Reviews Why Other Nations May Want to Move Away From the Dollar

U.S. Money Reserve Reviews Why Other Nations May Want to Move Away From the Dollar

May 13, 2025

The World’s First Operating System for Smart Cities

May 16, 2025
BMW Group sources aluminium produced using solar energy

Global solar PV growth expected to slow to 10% in 2025, reaching 655 GW new installations

May 6, 2025

The World’s First Operating System for Smart Cities

May 16, 2025
Brooklyn Park Man Pleads Guilty to His Role in $250 Million Feeding Our Future Fraud Scheme

Two Men Sentenced for Real Estate and Tax Fraud

May 16, 2025
Teacher arrested, charged with distribution and possession of child pornography

Army Soldier Charged with Child Pornography Offenses

May 16, 2025
Why Is Geographic Mobility Declining?

Why Is Geographic Mobility Declining?

May 16, 2025
Self-Made Millionaire at 14 Shares His Empowering Journey From Food Stamps to Financial Freedom

Self-Made Millionaire at 14 Shares His Empowering Journey From Food Stamps to Financial Freedom

May 16, 2025
ADVERTISEMENT

Popular Last 24h

  • Ampersand wins £22m five-year contract at London Zoo

    Ampersand wins £22m five-year contract at London Zoo

    3332 shares
    Share 1333 Tweet 833
  • Magical Night: Unique Hotels in Scandinavia

    685 shares
    Share 274 Tweet 171
  • The London Diplomatic List, Addresses, Contacts & Working Hours

    2995 shares
    Share 1198 Tweet 749
  • Two Men Sentenced for Real Estate and Tax Fraud

    30 shares
    Share 12 Tweet 8
  • U.S. Lifts Sanctions on Syria: How This Will Affect Recognition of Russia-occupied Territories?

    48 shares
    Share 19 Tweet 12
  • Global solar PV growth expected to slow to 10% in 2025, reaching 655 GW new installations

    85 shares
    Share 34 Tweet 21
  • The World’s First Operating System for Smart Cities

    39 shares
    Share 16 Tweet 10

LATEST POSTS

The World’s First Operating System for Smart Cities

May 16, 2025
Brooklyn Park Man Pleads Guilty to His Role in $250 Million Feeding Our Future Fraud Scheme

Two Men Sentenced for Real Estate and Tax Fraud

May 16, 2025
Teacher arrested, charged with distribution and possession of child pornography

Army Soldier Charged with Child Pornography Offenses

May 16, 2025
Why Is Geographic Mobility Declining?

Why Is Geographic Mobility Declining?

May 16, 2025
Self-Made Millionaire at 14 Shares His Empowering Journey From Food Stamps to Financial Freedom

Self-Made Millionaire at 14 Shares His Empowering Journey From Food Stamps to Financial Freedom

May 16, 2025
Why Board Portals Are Vital for Modern Businesses?

When Is the Best Time to Apply for a Business Loan?

May 16, 2025
HX5 Maintains Excellence in Mission-Critical Operations Through Navigating Regulatory Challenges

HX5 Maintains Excellence in Mission-Critical Operations Through Navigating Regulatory Challenges

May 16, 2025
How to Budget for a New Car Without Sacrificing Your Lifestyle

How to Budget for a New Car Without Sacrificing Your Lifestyle

May 16, 2025
U.S. Lifts Sanctions on Syria: How This Will Affect Recognition of Russia-occupied Territories?

U.S. Lifts Sanctions on Syria: How This Will Affect Recognition of Russia-occupied Territories?

May 15, 2025
Cyber risks are one of the biggest threats to the digital and networked economy

Munich Re posts net result of €1.1bn in Q1 despite high major-loss expenditure

May 15, 2025

LATESTBUSINESS

Brooklyn Park Man Pleads Guilty to His Role in $250 Million Feeding Our Future Fraud Scheme

Two Men Sentenced for Real Estate and Tax Fraud

by The FINANCIAL
May 16, 2025
0

Cyber risks are one of the biggest threats to the digital and networked economy

Munich Re posts net result of €1.1bn in Q1 despite high major-loss expenditure

by The FINANCIAL
May 15, 2025
0

Cryptocurrency Total Market Cap Jumped 80% After COVID-19 Crash

Confidence in regulation of the crypto and digital assets sector is rising, study

by The FINANCIAL
May 15, 2025
0

U.S. Money Reserve Reviews Why Other Nations May Want to Move Away From the Dollar

U.S. Money Reserve Reviews Why Other Nations May Want to Move Away From the Dollar

by The FINANCIAL
May 13, 2025
0

Thomas Priore Discusses How Unified Commerce is Transforming Business Financial Operations

Thomas Priore Discusses How Unified Commerce is Transforming Business Financial Operations

by The FINANCIAL
May 13, 2025
0

Homes Sold Faster than Ever in 2017

Tariffs Spur Home Improvement Shock: ‘Prices to Skyrocket,’ Expert Warns

by The FINANCIAL
May 7, 2025
0

Turkcell and Huawei Complete World’s First LTE Spectrum Coordination on a Commercial Network

Huawei Digital Power’s All-Scenario Grid Forming ESS Accelerates the Global Energy Transition and Construction of New Power Systems

by The FINANCIAL
May 7, 2025
0

PwC: Policymakers Must Offer Clarity and Coordination to Secure Net-Zero

PwC to Cut 1,500 U.S. Jobs as Part of Strategic Workforce Adjustment

by The FINANCIAL
May 6, 2025
0

GET IN TOUCH

Submit guest post/Letters to the Editor:

editor (at) finchannel.com

Sales & Marketing: (+995 558) 03 03 03 Email: marketing (at) finchannel.com

Whatsup: (+995 599) 96 52 52

Georgia:

(+995 599) 96 52 52 Email: editor (@) finchannel.com

Postal address: 17 Mtskheta str. Tbilisi, Georgia 0179 The FINANCIAL

RESOURCE

  • Work at the FINANCIAL
  • ePaper
  • Advertise in The FINANCIAL
  • Access ePaper
  • Guest posts
  • Contributed articles
  • AmericanStockNews
  • Coupon Codes
  • GLOSSY MAG
American Culture Center
ACC Partner

GUIDEBOOK

  • Meet our team
  • Invest in Georgia
  • Become contributor
  • Archive

FOLLOW US

  • Facebook
  • Twitter
  • Google+
  • Youtube
No Result
View All Result
  • Home
  • Business
    • BANKS
      • GeoBanks
    • Finance
    • Insurance
    • Markets
    • Pharmacy
    • Press Releases
    • RealEstate
    • RealEstate
    • Finance
    • Insurance
    • Banks
      • GeoBanks
    • Markets
    • Press Releases
    • Personal Finance
  • World
    • Americas
    • Europe
    • Georgia
      • Media
    • Ukraine
    • Europe
    • Georgia
      • Media
    • Ukraine
    • Americas
    • UK local news
  • Travel
    • Hotels in Georgia
    • Tours in Georgia
  • Videos
    • Promos
    • Soundslides
    • TheClinics
    • TheHoteliers
    • TheUniversities
    • TheHoteliers
    • TheClinics
    • TheUniversities
    • BestWorkplaces
    • Soundslides
    • Promos
    • Banking Forum
      • Promos
      • Soundslides
      • TheClinics
      • TheHoteliers
      • TheUniversities
  • Opinion
    • Editorial
      • Analysis
      • GORBI
      • OP-ED
      • VISA Editorial
    • Analysis
    • Gorbi
    • Book reviews
  • Tech
  • Interview
  • People
    • lifestyle
    • Health & Beauty
      • Coronavirus
    • LifeStyle
    • Employment
      • MyCareer
    • Education
    • Media
    • Celebrities
  • Oil&Auto
    • Auto
    • Energy
  • EN
    • EN
    • GE

© 2025 Intelligence Group llc

Welcome Back!

Login to your account below

Forgotten Password?

Retrieve your password

Please enter your username or email address to reset your password.

Log In

Add New Playlist

This website uses cookies. By continuing to use this website you are giving consent to cookies being used. Visit our Privacy and Cookie Policy.